What I would like to see happen is to let AoS finish out season 4 and then bring it back in the spring of 2018 as a special mini-series event. I'd like to see a 4-night crossover event with The Defenders leading into Infinity War. The Defenders Netflix series should air towards the end of 2017, so that team will be established prior to IW.
The plot could see SHIELD enlisting the assistance of The Defenders to tackle mysterious disturbances popping up around the globe. Mix up the teams for some interesting character interactions, as they each go out to confront what ends up being the very early onslaught from Thanos.
Alpha Team - Nick Fury, Hawkeye, Mockingbird, Deathlok, Daredevil
Bravo Team - Agent Coulson, Agent May, Luke Cage, Jessica Jones, Lance Hunter
Charlie Team - Agent Hill, Quake, Agent 13, Iron Fist, Mack
Others - Agent Fitz, Agent Simmons, Dr. Selvig, Dr. Cho
Film this in August of 2017 to air in late March 2018 for four consecutive nights, each night focusing on one team, with the climax the final night. This would probably need to leave Fury, Hawkeye, and Hill in a position to show up in IW, but that shouldn't be too difficult. Air this on ABC and then made available on Netflix immediately after. Pie in the sky idea, but it would be a cool way to get all of these characters involved in IW in some capacity.