Uncharted, Souls, Mass Effect, Valkyria Chronicles, Assassin's Creed, LBP, Heavy Rain, and Dead Space to a lesser degree than the others.
Uncharted will probably be the new IP I remember the fondest. There's not really anything I flat out dislike about it, but it gives me that nostalgic fun adventure feeling I get from the Indy flicks. The Soul's games are just unique, great atmosphere, and some of the best feeling controls this gen. I think Demon's especially will still be a game I think about next gen. VC is frustrating, because I loved 1, then they took the rest handheld...AC, and LBP I'm not going to say much on because they speak for themselves on why they stand out (now make LBP RPG Maker!). Heavy Rain, I think is another one that would be hard for me to forget, it was definitely a unique experience, and had a good story to boot. Dead Space I put as being to a lesser degree because I'm not huge into survival horror anymore. However I think it'll still be a series I look back on in a good light because it took over the gap in gaming left when I stopped caring about the Resident Evil series.
There are other new series I really liked, but I'm not sure they'll stick in my mind as a classic. Like the Arkham games. I like them, but I'm not in love with them like a lot of ppl seem to be. Dead Island really hit the nail on the head with zombies, but that's not a genre I'm always in the mood for. Resistance is kind of another, but fell flat. One was a lot of fun. 2 had some great big boss fights, and great co-op, but fell short in most other areas. With the bad word of mouth on 3, and the negative reviews, I don't even care to pick it up for sub $10 at GS.