First and foremost I want a charismatic actor for Lex. This Luthor has a likable public persona but is a real stone cold bastard behind the scenes, sometimes going as far as physically abusing right-hand woman Mercy Graves.
George Clooney
Tom Cruise
Brad Pitt
Leonardo Dicaprio
Matthew Mcconaughey
Denzel Washington
Bradley Cooper
Matt Damon
Hugh Jackman
Dwayne Johnson
Sylvester Stallone
Chris Pratt
Adam Sandler
Alec Baldwin
Bob Odenkirk
Dennis Leary
Jeff Goldblum
Donald Glover
John Cusack
John David Washington
John C. Reilly
John Krasinski
Eddie Murphy
Forrest Whitaker
LaKeith Stanfield
Sasha Baron-Cohen
Sterling K. Brown
Cuba Gooding Jr.
Pierce Brosnan
Ice-T
Tom Hanks
Casey Affleck
Adam Driver
Jason Bateman
Nicolas Cage is my number one pick for a few reasons. He has a huge screen presence with his own innate charm. He's an Oscar-winng actor with "massive" talent. He's a huge fan of Superman who was cast to play Superman, and that's an interesting meta- narrative. He's cheap these days too.