I don't know. When something new succeeds, there is this hindsight effect, which makes it seem like its success was inevitable, and that it therefore benefited from being the first.
But, back before Avengers succeeded beyond anyone's expectations, a lot of people were saying that it might just perform like an IM movie, and nobody really knew how a mash-up would be perceived by critics.
After Guardians of the Galaxy made a big splash, it became easy to rationalize that by saying stuff like, "people wanted something new and fresh," but going into it, there was really no guarantee that audiences would respond that way.
So, in this case, I'm not sure that simply being the first big budget superhero movie based on a female character, with a woman directing, was a big advantage.
That alone wasn't going to interest people, guarantee critical acclaim, or box office success.
Now that the movie has apparently delivered, it will be easy to say that it got a boost from that, but I'm not sure it was really an innate advantage. It's just going to feel like one now because apparently, instead of being a disappointment, the movie delivers an amazing experience that people can be excited about.