Yeah, Batman's life in general has always been incredibly depressing, I always think "return of the joker" or the episode "Epilogue" really made me realize how lonely Bruce would eventually become for many years.
It's odd I have such an odd crush on the guy, despite knowing his life sucks because of the expense of trying to be an insanely good person.
That's where I found it Interesting where Nolans' Batman took him, and why I think TDKR (Rises), was somewhat of a let down, I remember BB & TDK, was my favorite because it really felt like Batman would be doing it forever, it was his burden to bare.
Now, the new 52 animated films have brought in and made a much bigger impact of the "bat family" and showing this is Bruce's grounding, his purpose to live, and vice versa, they are a support system for each other, even despite Bat's dark ways.
I do get the feeling Reeves will really tap into this based on his comments, and I imagine "The Batman" will be about him re-uniting the "Bat family"
I really hope Death Stroke can stay as the villains, and there isn't a "main villain" in it. I think there's ample opportunity to have Leto re-prise his role, and develop his character along with Margot Robbie's Harleen Quinzel & Black Mask.
All which I think could have ample story related to the Bat Family.
The joker could be a reason the last Robin died, with Nightwing leaving due to Bruce's excessive use of force (seen in B vs S), Black Mask can be the connection to Bat Girl & I hope they go for Tim Drake but if its not and its Damian Wayne, Death stroke can easily be his mentor.
With Black Mask hiring a hit on the joker from death Stroke, I'd love to see Death Stroke show up to kill Joker, something we haven't really gotten in comic book films is a battle between villains where our Hero is in line to stop both.